30 Eylül 2012 Pazar

Day 1090 - Sacrotuberous Ligament

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"The sacrotuberous ligament is a slender, fan-shaped ligament of the posterior pelvis located on either side of the body. This ligament arises midway down the posterior side of the sacrum, which is located at the spinal base. It primarily comprises of collagen fibers, and is strong enough to support the sacrum and prevent it against moving from its position under the body weight.

The connective tissue in this ligament joins with various other tissues, particularly the biceps femoris muscular tendon, which is an important muscle of the hamstrings on the posterior thigh region. It is also a ligament of the sacroiliac joint, which is connected to the sacrum.

It typically receives stress during aggressive physical activities and sports that may cause the arching of the spine. If it becomes strained or injured, it may result in problems similar to those of a typical iliolumbar ligament injury. The ossified or bony sacrotuberous ligament may be one of the critical causative factors in different types of neurovascular compression syndromes. An anatomical understanding of this ligament may lead to effective treatments for this clinical disease."*

*http://health.yahoo.net/human-body-maps/sacrotuberous-ligament/male#4/8

I went to see the kinesiologist again at the beginning of the month. He focused on my back during our session, in particular on the lower part where the sacrotuberous ligament is. He looked for a link between this, the TMJ and the temporalis fascia, which is exactly where my head pain is. He told me he had to work on my lower back for a few minutes. I could tell it was going to be painful but I hadn’t quite realised up to what extent.


The pain was excruciating. I felt my hands begin to tremble and suddenly tears starting flowing down my cheeks. At first they were tears of pain but soon, even when he completely stopped exerting pressure, I was unable to stop crying. I was overwhelmed with sadness; my body trembled and I sobbed and sobbed. I tried to hold myself but simply couldn’t. I don’t know what it was; the only way I can explain it is complete sadness, although for what reason I do not know (women out there may sympathise with those occasional moments when we just cry for no reason –men may find this impossible to understand).


The kinesiologist explained that when working on certain areas of the body blocked emotions can be released. These could be from traumatic events in childhood or other moments of extreme stress that one has had to deal with. It was hard to pinpoint an exact instance of this at the time.


Despite the feelings of despondency and confusion, I felt that maybe during this session we had another clue. It was the first time I had reacted in such a way during any of our appointments – the poor kinesiologist was surprised at my response to his work – and felt that maybe it was a sign we have found something.


Since then, the headache has been up and down – the first time in about a year that it has been up to 4/5 for longer periods – which makes me think that, despite the increase in pain, we may be one step closer to a solution.

Day 1121

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The three year headache anniversary passed unnoticed – or should I say ignored. One year, two years, three years.. it nearly seems to make no difference anymore. It’s been dragging on for so long that my hope that it will cease is waning.

I wish those who didn’t suffer from this wretched thing could understand how awful it is. Having a constant headache is so tiring, it makes the world so much heavier, every moment drags on for so much more, even when it's a fun moment, it's always somehow ruined because nothing is ever perfect, there's always that horrible headache reminding me that something is wrong.

One of my greatest passions is reading and yesterday, as I was reading a book, I had to stop for a while as the headache – for whatever inexplicable reason – was quite strong at that moment and it made it hard for me to concentrate. So the headache is always there, reminding me of its presence (don’t worry, I won’t forget you, dear) at every moment. Even when I have a few moments to myself, to sit back and relax, the headache topic inevitably comes up. I question it but soon get tired as I have no answers, and try to brush it aside.

I have learned to try and not ponder too much on its presence, to try and get on with daily life as much as possible and not let it interfere with my life, but the truth is that at times when I go to bed, I sometimes wonder ‘What if I just don’t wake up tomorrow?’ The truth of the matter is that, as much as I can ignore it, I realise that it is not normal to have had a headache for three years and sometimes I worry that the wretched thing may play its final joke on me.

Day 1214

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Just yesterday I spoke to someone over the phone and asked him how he was. “Just a bit of a headache today”, was his answer. Needless to say, all kinds of thoughts flashed through my head. I could not bring myself to say “Oh, sorry to hear”, as one would normally do. I just brushed it aside muttering some sort of a “I understand” under my breath. I find it impossible to empathise with people who have ‘a bit of a headache’ – if only they knew.

I must admit I have become more and more secretive about the Headache. When It started I told virtually everyone about It, hoping that someone along the way would have an acquaintance with a similar story and know about a miraculous cure; but as time has gone by, I have not dared tell any new friends. The only people who currently know about It are those whom I had originally told.

In my mind there is a stark division: the before and after It started - those who knew me already, and those whom have only known me with a headache (much to their ignorance). I sometimes wonder if they would think of me any differently if they had met me before.

As a reader of this blog rightly suggested, having our headaches has undoubtedly led us all to explore different paths in life. In a way, there are many new and different areas that I have looked into to find a cure. I have learned and assimilated so much new information that I would certainly not have acquired otherwise; but I can’t help thinking how much better my daily life would be without this witch of a Headache, without having to open my eyes every single morning and have the side of my head pressing in – a wonderful reminder that it is always there.

Day 1285 - It's All In Your Head

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"Many people know about other contributing factors such as heredity, food triggers, lack of sleep, poor posture, etc., but are not aware of any psychological connection.
Headache specialists report that many of their patients resist any discussion of emotional or psychological contributors to their recurrent headaches. Some people fear that pursuing this avenue could uncover evidence of "mental illness." Others feel that the existence of these factors would make their pain less real because it would then be "all in their heads". In just about all cases, neither of these 2 things is true!

Headache is definitely a biological disorder. However, since the body and the mind are interconnected, your emotional and psychological states can have an effect on your overall health, including your headaches. Here's why:

- When your emotional and psychological systems are in good working order, they help to create a positive environment that contributes to the health of your body.
- When these systems aren't working so well...for example, if you feel anxious, depressed or angry on a frequent basis — and especially if you find it difficult to shake these feelings — a negative environment can be created in your body that may contribute to a specific headache episode or create a fertile breeding ground for headaches to occur.

The relationship between anxiety, depression and headache is not fully understood. However, it is known that the brain chemical serotonin plays a role in all of them. Some headache specialists have theorized that these disorders may share a common mechanism in the brain.

Research has shown that some chronic headache sufferers also suffer from depression and/or anxiety. It is important to note that these sufferers' psychological conditions may not be caused by their headaches. Rather, tendencies towards depression or anxiety may be inherent in their personalities or ways of thinking. Or, they may be the result of an intense and prolonged level of stress which may lead to psychological conditions such as anxiety or depression. Regardless of the cause, having frequent headaches and feeling a lack of control over them may cause an existing condition of depression or anxiety to worsen. This situation can easily snowball, creating a vicious cycle of headache and emotional distress.

Unfortunately, emotional and psychological factors are often not considered in the treatment of headache. Doctors (especially those who are not headache specialists) tend to emphasize medical treatment — and rightly so. This is the traditional "first line of defense" and is effective for most headache patients. So is appropriate to start — and, for most, to stop — there. Also, some doctors today are cautious not to focus on psychological factors during the earlier stages of headache treatment — possibly overcompensating for the days when many doctors treated patients as if the pain was "all in their heads."
Doctors who do bring up psychological contributors as a possibility often find that their patients want to avoid psychological treatment, fearing a "mentally ill" diagnosis or having a concern that the presence of these factors would mean that their headaches are not a serious medical problem. This is very unfortunate because nothing could be farther from the truth!"*
*http://www.excedrin.com/psychological-contributors-to-headaches.shtml


It has taken me over three years to write this post.

When the headache started - which now seems all those years ago - I went to see a psychologist about it. The headache had exacerbated to such a degree that I was unable to work and felt completely depressed about my situation. After telling her about the distress that the headache had caused, she looked at me, arms gently folded over her lap, and stated “It must be such a headache having this pain!” and gave a little chuckle. I brushed aside this silly joke, ignoring it and thinking that maybe she had unintentionally let it out. However, when the very same joke repeated itself over the course of the next sessions, I felt hurt, frustrated and angry that a person contending to be there to help could actually end up aggravating a situation. I could bear it no longer and after a few sessions I left. That was the last of any psychological treatment I have undergone.

The possibility of the headache being related to a close friend’s death which took place a few months before the onset of my headache, has crossed my mind more than once. But nearly four years down the line I do not think the headache is related to this, or at least entirely to this. It is possible that I have not yet recovered from the shock of losing such a close friend. I truly believe there is a strong link between body and mind and that a traumatic event can undoubtedly have consequences on one’s body. The passage above taken from a Headache Centre webpage discusses this in further detail. Just today I also came across an article on the BBC website on a similar topic.

The reason it has taken me so long to write anything on this is that I am unable to draw the line between the “it could be a psychologically caused headache ” to a “it’s all in your head” (i.e. fictional). I am certain, from the manner in which this question is usually addressed to me, that by ‘psychological’ the word ‘fictional’ is intended. Does anyone feel the same?

Day 1342 - Viscountess Anne Conway & The Headache That Lasted For 48 Years

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When my sister sent me the above photo Iimmediately asked her where she had taken it. Oddly enough, her answer was ‘Ina museum’. I immediately Googled “Viscountess Anne Conway + headache” and soondiscovered that Anne did indeed suffer from a mysterious headache for virtuallyall her life. She died in 1679.
I wonder what people thought of herheadaches back then. Did they think she was a hypochondriac? A liar? A witch?An emotionally unstable, neurotic woman in need of some fresh sea air?
Anne was actually a highly respected 17thcentury philosopher, metaphysicist and intellectual whose ideas and criticismson Descartes and Hobbes influenced later writers.
Her debilitating chronic headaches arementioned in a number of sources. From what I have researched, I am unable tosay whether Anne suffered from one persistent headache or a series ofcontinuous attacks. It seems to me it was probably one continuous headache, butgiven that most people do not even believe such a thing possible, over time I thinksome physicists and historians may have eventually settled for ‘headaches’ inthe plural.
Her severe headache perplexed friends anddoctors alike, leading her to try all sorts of (dangerous) cures includingmercury and opium, albeit to no avail. In a desperate attempt to cure theheadache, Anne even travelled to France to be trepanned. No one dared proceedwith the operation and eventually her jugular arteries were opened instead – anequally risky procedure. A renowned alchemist and healer was even invited toAnne’s country home to try and rid her of the debilitating pain, but herheadache persisted. It continued to baffle eminent physicians and doctors forthe rest of her life.
It appears her headache started at the age of 12.It was initially attributed to her excessive studying habits, although a number of sources claim it started following a severe illness accompanied by fever, whichleft a lingering headache that continued for the rest of her life.
The headache had a clear influence on herlife and ideas:
“Theway her own suffering from increasingly debilitating headaches contributed tothe development of her philosophical assessment of pain as an integral part ofthe process of purification adds an autobiographical element to her writingthat is all too often ignored in the analysis of philosophical systems.”***
  Anne was not considered mad, mentallyunstable or neurotic given her constant headache and pleas for help. If onlyour doctors, like those four centuries ago, believed us when we say we sufferfrom a continuous headache that never goes away.
* http://oregonstate.edu/instruct/phl302/philosophers/conway.html **http://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=11&ved=0CD8QFjAAOAo&url=http%3A%2F%2Fwww.sunypress.edu%2Fpdf%2F61627.pdf&ei=5cgzUNrrGYfFswaX9YCwDg&usg=AFQjCNHCa6s3Ei64Hef225RGkcG2C17f3w***http://www.scribd.com/doc/76534622/Anne-Conway-E3P1DBdnZv

29 Eylül 2012 Cumartesi

Healthy Lungs Tips - Surely will help you

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Breathing is one of the most crucial functions carried out by the lungs.

Each and every breath taken by the lungs adds oxygen to the body and expels carbon dioxide.

They also protect the body from the harmful effects of the environment like infections and pollution.

Milk thistle or silymarin extract helps the lungs in fighting against toxins found in the environment.

There are many benefits of drinking green tea. It is highly effective in protecting the lungs against the development of cancer.

Avoid smoking or exposure to second-hand smoke. Smoking is the leading reason behind the development of lung cancer.

Avoid second hand smoke. If anyone smokes close to you, it is best to leave the area or ask them to stop smoking.

Patients who are dealing with lung cancer should seriously avoid second hand smoke as it can aggravate their condition.

Exercising is a good way to have healthy lungs. You can include running, walking, swimming and other cardiovascular exercises in your schedule to improve the functioning of your lungs. The more you exercise, the stronger your lungs will become.

It is also essential that you consume a nutritious diet in order to have healthy lungs. Different food types to eat should include:

Cereals, grains and breads that are high in fiber content.

Lean proteins like fish, eggs, turkey and chicken.

Sufficient amounts of water as it also helps in flushing out toxins.

You should avoid consuming excess amounts of oily food, salt, alcohol and caffeine. It has been found that proper nutrition and dietary habits have a strong effect on the functioning of lungs, and avoiding unhealthy foods can also help in avoiding lung diseases. In fact anti-inflammatory and anti-oxidant rich food has been found to be helpful in improving lung function and minimizing the development of lung diseases.

Avoid working in environments where there is excessive amount of particulate matter in the air. For example, people working in textile factories are prone to contracting Byssinosis caused due to intake of cotton and other dust particles.

Natural Yeast Infection Remedies - They will really work

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Yeast Infection is common disease for both women and men.

Water is the most natural and important substance that we need to give our bodies.If do not have enough water it can contribute to the onset or worsening of almost any condition.

In the specific case of yeast infection drinking enough water will help to flush out the unwanted sugars in the system that feed the yeast.

Plain yogurt is a very effective natural remedy for this condition.The bacteria in the plain yogurt fight the yeast and help to bring the infection under control.

It can be used internally and externally, but it really must be plain, sugar free yogurt.

If you make the mistake of using yogurt with sugar you may actually feed the infection and make it worse, so please be careful.

One way to ensure your yogurt has only the ingredients you want is to make it yourself specifically as a remedy.

This way you can ensure that there are no unwanted additives in the mix.

Garlic , most people find it to be a really quick and effective remedy and like water and yogurt is easy to get hold of.

Applying it to the affected area can provide almost instant relief from the irritation you are experiencing from the infection.

It is best to used fresh garlic puree but you can buy garlic tabs from health shops. Either way garlic will provide great and quick results.

Apple Cider Vinegar - For this purpose it is best to put some into a hot bath and it will have a very soothing effect on the irritated area.

Child Colds Flu Treatments - Effective Natural Remedies will surely help you

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(1) Make sure your kids are getting plenty of sleep. This is when their body heals and regenerates the most, so getting adequate rest is vital to staying healthy.

(2) Have them drink plenty of water. Hydrating keeps toxins from building up in your system and helps to flush them out of the body.

(3) Try and monitor your kids' stress levels. Stress depresses your immune system, so with increased and sustained levels of stress, there is a greater chance of becoming ill.

(4) Decrease sugar in the diet. Limit processed foods, pastries, candies, etc. as sugar also impairs the immune system and your overall ability to fight colds and flus.

(5) Make sure they are playing or exercising regularly. Moving your body increases your circulation, helping to move blood and lymph along.

This allows your white blood cells to circulate and fight germs better. Increasing blood flow also flushes toxins away from muscles and organs, and sweating from exercise or play also removes toxins through the skin.


(6) Have your child continue to drink more water and get plenty of rest. These are still the best ways to help support our body's natural defenses and give our body a greater opportunity to fight off any infections.

(7) Take out sugar completely and decrease mucus-producing foods, such as dairy, citrus, and bananas. This will lessen the load on the immune system and prevent any congestion from becoming worse.

(8) Echinacea and elderberry are some great herbs that can help boost the immune system and combat upper respiratory infections.

The gylcerite forms of these herbs are also tasty for children.


(9) The wet sock treatment is very helpful for increasing circulation and decreasing congestion in the head, throat, and chest. It also helps with sleep and stimulates the immune system (procedure for a wet sock treatment found below).

(10) Other herbs that are warming and good for colds and congestion include cinnamon, ginger, cloves, and yarrow. They can increase circulation and help stimulate body heat.

(11) Chamomile tea is wonderful for children because it relaxes them so they can sleep while also helping to clear coughs and congestion and decreasing fever.

(12) Taking horehound and mullein internally are good for clearing bronchial congestion by stimulating coughs. Mullein is also an antimicrobial to help fight infections.

(13) Another Healthy Living Tips 2011 for this type of Flu that "Thyme and Eucalyptus essential oils can be added to 1 ounce of olive oil to rub behind the ears, down the neck, and on the chest before your child goes to bed or upon waking. The essential oils can also be added to steam showers or a big basin of hot water for your child to inhale to relieve the congestion."

(14) Vitamin C and zinc stimulate the immune system and help to both prevent and reduce the duration of colds.

(15) Fish oil also helps modulate the immune system and decreases inflammation.

Medications Side Effects – Tramadol Simvastatin Metformin

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The
side effects of medication are far more serious than most people realize.

Here I want to talk especially about three medications which I recently read online at one of the famous online health forum sites.

Tramadol: - It could be the right pain management medication for treating your pain.Its similar to Codeine used to treat moderate to moderately severe pain when treatment is needed around the clock. It does work best if your pain is not too severe. For severe pain a stronger medication may be needed.

It’s also known with various names Tramal, Ultram, Mabron, Ralivia, Ryzolt, Tradonal, Tramacet, Tridural, Ultracet, Zamadol, Zydol, & Zytram.

It should be taken properly while following the prescription instructions so as to avoid serious side effects or even death.

Side Effects of Tramadol:-

Constipation, nausea, vomiting, dyspepsia, occasionally diarrhea, Somnolence, itching, dizziness, sweating and flushing

Simvastatin: - It’s also known as Zocor, used to treat high cholesterol, and may be used in conjunction with diet changes recommended by your doctor.

Side Effects of Simvastatin:-

It should not be given to women of child bearing age who may become pregnant without excellent contraception and a strong indication.

Others are like weakness, muscle pain, excessive aching or pain after physical exertion, or just vague pain all over, liver related issues including elevated liver transaminases and elevated creatine kinase, abdominal pain, constipation, flatulence or diarrhea.

Metformin: - Its best choice for type 2 diabetes - non-insulin dependent.

Its oral medication that assists in controlling the sugar levels in the blood can be used in combination with insulin or other supplements.

It can also be used in treating polycystic ovary syndrome but people who are prescribed to take this medication are required to undergo regular blood sugar level determination. Although it does not cause the blood sugar level to drop drastically it may cause severe hypoglycemia if used in combination with other anti-diabetic medications.

Metformin Side Effects:-

Lactating women should also avoid it since it may pass into their breast milk.If you are pregnant or planning to get pregnant and you are taking this medication, you should inform your physician the soonest possible time.

Nausea, vomiting, abdominal pain, diarrhea and loss of appetite are the most common that it affects more than 1 in 10 people.

Very rare side effects are lactic acidosis, reduced vitamin B12 absorption with chronic use, and skin reaction like itching, flushing or rash.

Effective Foods for Healthy Hair

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A balanced diet with mineral like iron, calcium, potassium, selenium, magnesium etc. is perfect natural solution hair loss cause in women, plays important role for healthy hair and scalp, with your external haircare which contains various shampoo, conditioner, keeping the scalp clean etc.

Why protein also important?

Because its crucial for better healthy hair growth, low-quality protein can produce weak and brittle hair, and can eventually result in loss of hair color.

(1) Whole grains have more nutrients per unit than their refined counterparts.

Add to this the large quantities of fiber they have which makes them really good for our digestive system.

They can be easily digested, contain a lot of antioxidants and help keep chronic diseases like cancer, diabetes, obesity and constipation at bay.

(2) Vitamin C

Its brimming with collagen, a protein which helps in maintaining hair follicles, blood vessels and scalp.

Fruits like oranges, lemons, pineapple, strawberries, guava etc are great sources of it.

Green leafy vegetables also contain vitamin C and iron which is another great nutrient for healthy hair.

(3) Brown Rice

It is a good source of protein, vitamins and fibre, gives your hair the shine you’ve always wanted. makes you feel full for longer durations and helps suppress your hunger pangs.

(4) An ½ cup serving of dal can easily offer about 6 gm of protein.

Besides, dals are rich in minerals like potassium and magnesium.

However, you should not solely depend on dal for your daily protein intake.

(5) Calcium is also a key nutrient for maintaining hair health, makes your hair shine and not to forget that it also gives you healthy, stronger bones.

Now a lot of calcium is used up by daily wear and tear and one needs to consume adequate calcium-rich foods to replenish lost calcium.

Dairy products are excellent sources of it.

28 Eylül 2012 Cuma

Effective Home Remedies to get Dengue That Work

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Dengue fever is one of several infected viral disorders spread over the mosquito bite. The female Aedes aegypti mosquitoes thrive with stagnant drinking water regarding surroundings plus grow to be this companies belonging to the virus. The disease is characterized by minor to substantial fever, headache, mutual in addition to muscle mass cramping along with rashes. Dengue a fever is usually also known as the particular bone fragments splitting fever, as a result of severe ache knowledgeable while in the your bones plus muscles. Mild Dengue fever doesn't pose any kind of considerable threat, but the condition may become worse inside the dearth associated with suitable medications. Hemorrhagic Dengue causes internal blood loss and will bring on death. Dengue a fever could be determined from the indicators in addition to body exams within a couple of days with the particular fever. Symptoms Dengue intense is often determined with the next symptoms 1. Mild to help higher a fever related to 105 F 2. Severe discomfort inside the bone joints 3. Intense headache plus backache 4. Loss of appetite 5. Appearance with rashes all over the body 6. Nausea as well as vomiting Prolonged abdomen ache, anal plus nasal internal bleeding are generally the symptoms regarding Hemorrhagic Dengue Causes Dengue a fever is caused coming from the particular bite regarding feminine Aedes mosquitoes. These mosquitoes type inside clean, stagnant waters while in the surroundings belonging to the home and also multiply the an infection to a number of people today from the locality. People, whom don�t take sufficient defense from the particular mosquito bites, will likely are afflicted by this specific disease. Home Remedies regarding Dengue Some practical homemade remedies can be of wonderful assist in managing Dengue. 1. google_ad_client = "pub-2311940475806896"; /* 300x250, established 1/6/11 */ google_ad_slot = "0098904308"; google_ad_width = 300; google_ad_height = 250; One ought to reduce this vulnerability that will mosquitoes in terms of possible rather than opportunity away while in the dawning or perhaps dusk, if your mosquitoes are a lot of prevalent. 2. Mosquito nets, mosquito repellant creams along with coils must often be regularly applied although resting from night, to prevent this mosquito bite. 3. Holy basil finds are very beneficial throughout preventing as well as the treatment of dengue. Drinking your decoction connected with tulsi departs as well as cardamom powder, adding small sodium in addition to milk facilitates lowering higher fever. 4. Juice extracted through a couple of raw papaya leaves can be useful for stopping Dengue. 5. Drinking number of mugs pf natural tea equipped from tulsi leaves, ginger and cardamom powder can be quite helpful with reducing the fever. 6. Orange charge is widely used regarding the treatment of Dengue fever. Drinking lime juice allows in good digestion, improves urination and improves our bodies defenses procedure to combat the particular disease. 7. Plenty involving normal water as well as diluted fruit flesh power should become gave into the affected individual in order to maintain the desired water equilibrium on the body. Read more with regards to Home Remedies pertaining to Dengue. Also find out powerful Home Remedies pertaining to Ear Infection. Read useful Home Remedies for Gastritis.



Effective Home Remedies for Dengue That Work

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Dengue a fever is usually one of several catching viral illnesses propagate through the mosquito bite. The women Aedes aegypti mosquitoes prosper in flat mineral water associated with surroundings along with become your carriers of the virus. The ailment is actually portrayed by light that will substantial fever, headache, mutual and muscle aches as well as rashes. Dengue a fever is additionally known as the particular bone breaking fever, as a result of acute ache knowledgeable within the bone fragments as well as muscles. Mild Dengue curse will not pose any kind of considerable threat, nevertheless the issue could worsen from the absence with correct medications. Hemorrhagic Dengue creates interior bleeding and may bring about death. Dengue temperature might be diagnosed with the indications plus body tests with a couple of days in the fever. Symptoms Dengue a fever might be determined through the examples below symptoms 1. Mild to help large fever with regards to 105 F 2. Severe problems in the bone joints 3. Intense annoyance in addition to backache 4. Loss with urge for food 5. Appearance connected with rashes everywhere in the system 6. Nausea with vomiting Prolonged stomach ache, anal plus nasal blood loss include the signs or symptoms associated with Hemorrhagic Dengue Causes Dengue curse is definitely brought about on the chew of woman Aedes mosquitoes. These mosquitoes type within clean, stagnant water in the surroundings belonging to the household and also spread that contamination to your number involving people today while in the locality. People, whom don�t require adequate protection from the mosquito bites, may very well put up with this specific disease. Home Remedies with regard to Dengue Some handy homemade remedies may be associated with great assist in getting rid of Dengue. 1. google_ad_client = "pub-2311940475806896"; /* 300x250, created 1/6/11 */ google_ad_slot = "0098904308"; google_ad_width = 300; google_ad_height = 250; One will need to lower the direct exposure that will mosquitoes where probable and never enterprise out there from the beginning or perhaps dusk, if your mosquitoes are usually most prevalent. 2. Mosquito nets, mosquito repellant ointments in addition to coils has to be on a regular basis utilized while sleep at night, to counteract the actual mosquito bite. 3. Holy basil finds will be very helpful inside protecting against in addition to healing dengue. Drinking your decoction regarding basil departs along with cardamom powder, adding small sodium and milk assists with lowering higher fever. 4. Juice removed from two natural papaya leaves facilitates keeping Dengue. 5. Drinking couple of cups pf organic tea geared up out of tulsi leaves, ginger and cardamom powder can be quite useful in lowering the particular fever. 6. Orange fruit juice is actually widely applied with regard to managing Dengue fever. Drinking lime power helps in appropriate digestion, boosts urination and increases the particular body defenses technique to fight the disease. 7. Plenty connected with drinking water and also diluted berry fruit juice must be administered towards sufferer to keep up the actual required normal water equilibrium from the body. Read more related to Home Remedies intended for Dengue. Also find out helpful Home Remedies intended for Ear Infection. Read helpful Home Remedies intended for Gastritis.



Dengue Causes plus Symptoms plus Natural Home Remedy Treatment with regard to Dengue Fever

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Dengue temperature is really a disorder attributable to your family connected with viruses that are carried by way of mosquitoes. It is a strong acute condition of unexpected onset of which commonly comes after a not cancerous training course with symptoms for example headache, fever, exhaustion, acute muscles as well as mutual pain, inflamed glands (lymphadenopathy), and rash. The profile (the "dengue triad") connected with fever, rash, plus annoyance (and some other pains) is mainly feature connected with dengue. Other symptoms involving dengue a fever include blood loss gums, severe ache behind this eyes, and red palms plus soles. Read much more on Home Remedies for Heart Diseases and Home Remedies regarding Jaundice as well as Herbal Home Remedies What will be the Symptoms associated with Dengue Fever? Symptoms of usual fuss-free dengue normally start within just 5 to a few days to weeks once a person has already been bitten by simply an attacked mosquito. Some common signs and symptoms are: 1. High fever 2. The intense could reach 105 levels Fahrenheit 3. Severe headache 4. Pain driving the actual eye 5. Severe synovial pain 6. Severe muscular pain 7. Nausea 8. Rash Treatment at your home in case you produce dengue fever 1. Take rest 2. Drink plenty of fluids similar to dental rehydration solution, fresh new juice, soups, coconut water. This will easily prevent dehydration as a result of vomiting as well as substantial fever. 3. Take the medicines recommended by simply ones doctor. 4. Do not take aspirin and also additional nonsteroidal anti-inflammatory drugs, including ibuprofen. These prescription drugs add to the risk connected with hemorrhage complications. 5. Do tepid sponging if your intense can be high NATURAL HOME REMEDIES FOR DENGUE FEVER: 1. Mix a few spoons with making cookies soft drinks that has a little water; smear on sting. 2. Rub the afflicted location with the on the inside of a banana skin. 3. Put ice immediately immediately soon after currently being stung. 4. Apply tea tree acrylic on the sting. 5. Put many toothpaste to the mouthful (not on the skin). 6. Squeeze basil finds and also apply on sting. 7. Rub some lemon on the actual sting. 8. Saturate some sort of cotton tennis ball inside vinegar and also put on the particular sting. 9. To eliminate mosquitoes: Drip a few drops connected with geranium oil in to a burner.



Dengue Fever - Signs in addition to Diagnosis

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Dengue temperature is a mosquito-borne viral an infection several fever, generalized shape ache plus with extreme cases the item may perhaps also cause alternative and central bleeding.Dengue a fever generally develops while in the tropics and also subtropics regions involving world. Mostly it can be associated with Southeast Asia nonetheless practically it is becoming more widespread inside Central as well as South America. Dengue a fever is caused by a virus and distribute by means of mosquitoes.The Signs and Diagnosis regarding Dengue FeverSymptoms with Dengue fever contain fever, headache, and also acute generalized body aches, specifically in the legs, to come back along with joint capsules and so are worse in adults. These pain are often thus unpleasant how the illness is additionally also known as break up bone fever.Dengue Hemorrhagic Fever Dengue hemorrhagic temperature (DHF) is usually a distinct predicament of which usually affects kids underneath population involving 10 years. It will cause abdominal pain, bleeding, and circulatory shock. Dengue hemorrhagic curse is additionally identified as Dengue shock syndrome.Dengue fever sounds having clues regarding high intense along with headache. There usually are respiratory as well as digestive tract symptoms together with signals involving sore throat, cough, nausea, vomiting, and tummy pain. Shock comes about two in order to six days following your begin connected with symptoms with unexpected collapse, cool, clammy extremities, drained pulse, and blueness throughout the mouth.Patients with Dengue a fever must be with declaration for your starting up couple of days considering that distress could manifest or perhaps reoccur. google_ad_client = "pub-2311940475806896"; /* 300x250, made 1/6/11 */ google_ad_slot = "0098904308"; google_ad_width = 300; google_ad_height = 250; Bluish people pick up oxygen. Immediate liquid replacement is necessary within vascular collapse. To handle bleeding Blood transfusions can be needed.The rate involving death rate using Dengue hemorrhagic fever is usually considerable varying from 6%-30%.DiagnosisDiagnosis involving dengue pathogen virus is frequently created to the base of healthcare sings and also symptoms which is possibly not reliable. The basic graphic is definitely substantial intense devoid of localizing cause of infection, a compact purplish rash over a entire body exterior by using somewhat reduced platelet plus white wine blood cell count.Dengue diagnosis should always always be verified by laboratory tests, simply because more than 50 percent of attacked people either are generally asymptomatic or have a very mild undifferentiated fever.Laboratory diagnosis associated with dengue malware illness is often made by the recognition associated with particular virus, viral antigen, genomic sequence, and/or antibodies. Early prognosis of Dengue virus infectivity is complete simply by detection with dengue viral antigen in peripheral blood mononuclear cell.



Dengue fever along with Unani medicine

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Dengue intense is usually a new disease the result of a household of trojans which are carried by means of mosquitoes. It is definitely an acute condition with sudden attack that will typically comes after a not cancerous program by using indicators such as headache, fever, exhaustion, severe muscle and synovial pain, swollen glands as well as rash.The reputation (the "dengue triad") of fever, rash, and also headache(and alternative pains) is usually especially typical regarding dengue. Other symptoms connected with dengue temperature include hemorrhage gums, severe pain powering the particular eyes, and crimson palms and soles. Dengue (pronounced DENG-gay) strikes of those with lower quantities with immunity. Because it will be attributable to one with several serotypes associated with virus, the idea can be performed to get dengue a fever a number of times. However, a strong episode involving dengue generates immunity for lifelong to the next particular serotype to which the patient has been exposed. Dengue goes additional names, including "breakbone" or "dandy fever." Victims of dengue usually have contortions as a result of intense bowl and muscles pain, for that reason the actual brand breakbone fever. Slaves while in the West Indies that developed dengue had been told have got dandy temperature for the reason that health of their postures as well as gait. A last year herpes outbreak regarding dengue a fever in Key West, Fla., showed which some patients who seem to wouldn't travel beyond your U.S. contracted the actual virus. Subsequent testing on the human population of Key West offers established which as long as fifty five with the men and women living in the actual spot have antibodies to dengue. As associated with July 17, 2010, 17 individuals have also been determined in which acquired dengue throughout Key West in 2010. Dengue fever is actually common, and also research demonstrate it could be escalating in Southeast Asia. google_ad_client = "pub-2311940475806896"; /* 300x250, designed 1/6/11 */ google_ad_slot = "0098904308"; google_ad_width = 300; google_ad_height = 250; Thailand, Vietnam, Singapore, and Malaysia have just about all described a strong maximize inside cases. According into the U.S. Centers for Disease Control along with Prevention (CDC), you can find approximately hundred thousand cases associated with dengue curse together with several $ 100 or so million cases regarding dengue hemorrhagic fever requiring hospitalization just about every year. Nearly 40% of this planet's human population lives inside a space endemic with dengue. How could dengue fever possibly be prevented? The transmission with the trojan in order to mosquitoes have to be cut off to counteract this illness. To that end, clients usually are placed under mosquito netting until the second attack associated with fever has over and they should contagious. The prevention associated with dengue requires manage or maybe eradication of the mosquitoes holding the herpes simplex virus that involves dengue. In countries stricken by dengue fever, individuals are urged in order to empty flat water through older tires, cash cans, and blossom pots. Governmental initiatives to decrease mosquitoes likewise help to keep that disorder in check nevertheless have been poorly effective. To avoid mosquito bites, dress yourself in longer shorts and also much time sleeves. For private protection, work with mosquito repellant sprays which contain DEET when traveling to locations exactly where dengue is endemic. Limiting direct exposure to help mosquitoes by way of preventing standing up drinking water and lodging in the house a couple of a long time after sunrise along with ahead of sunset will help. TheAedes aegyptimosquito is a regular biter along with peak times associated with biting down hard close to sunrise along with sunset. It may bite whenever they want of the morning as well as being typically undetectable indoors households or even some other dwellings, especially within urban areas. There can be at this time simply no vaccine readily available dengue fever. There is often a vaccine starting medical trials, however it is definitely prematurily . to inform in case it will likely be protected or effective. Early effects connected with professional medical tests show that your vaccine may perhaps be available by 2012. Unani Treatment Sheerah Tukhm Khurfa 10 gm throughout standard water is valuable within dengue fever. Qurs Tabaseer with sharbat bazoori forty five ml Sharbat Deenar 40 ml 2 times daily Sharbat Tamarhindi 40 ml by using arq Gau zaban one hundred ml a couple times Habbe Shifa 2 hook a pair of times Afsanteen 6 gm, chiraita 6 gm, karanjwa 6gm decoction two times daily before supper very beneficial.



27 Eylül 2012 Perşembe

DENGUE VIRUS

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When the actual planet received initial man, the idea must welcome countless diseases. With the actual penetration of their time around the one hand society what food was in development as well as about the other hands disorders were being inside the progress. Up until finally today unusual amount of conditions continues to be witnessed by means of this human being. The diagnoses process likewise required beging with the start regarding health conditions and also still the two around progress. Some conditions have become task for that diagnostic teams. Some diseases safe place been clinically determined because of the diagnostic teams soon after very difficult and also wonderful do the job however your medication and also medications regarding such diseases couldn't often be found. Some health conditions from their names and also causing pathogen looked at being not difficult but our own common sense will be showed clearly entirely a new blunder. Because of some of our carelessness more rapidly that they develop into lethal and beyond healing range as well as patient, verts death is a supreme result. DENGUE FEVER OR DENGUE HEMORRHAGIC FEVER is likewise a major disease. By its title we think of the idea a run-of-the-mill fever owing for you to bite of a mosquito. Moreover you can find similarity somewhere between the actual signs with DENGUE FEVER and also regular seasonal fever. In the two cases symptoms are headache, bone fragments ache, muscles and joints pain in addition to fever. As each curse offers concerning the exact same symptoms, affected person would not look at it DENGUE whenever no these kinds of instance has been still reported coming from just about any quarter. Prior that will news about the DENGUE FEVER, none patient neither physician will take soreness to be able to diagnose your fever towards the magnitude with perfect diagnoses. ABOUT DENGUE VIRUS AND FEVER. Dengue a fever is an extremely outdated disorder but during last 20 several years that taken care of areas in excess of earlier. Dengue curse may be the result of the catch of an infected mosquito who may have injured earlier an infected person. google_ad_client = "pub-2311940475806896"; /* 300x250, made 1/6/11 */ google_ad_slot = "0098904308"; google_ad_width = 300; google_ad_height = 250; Dengue pathogen seriously isn't a infectious just one plus does not traveling originating from a individual to a further directly, between the 2 persons a mosquito could be the cause with contamination . Initially a man feels this they are suffering from flu because of the symptoms would be the same. Further when dengue hemorrhagic intense blasts the patient feels severe seasonal fever. Dengue intense is deadly one . Same as flu it is just a viral disease. Four sorts of dengue malware are actually observed so intended for that have been called since DEN-1, DEN-2, DEN-3 as well as DEN-4. AREAS OF VIRUS AND FEVER. Particularly the actual dengue fever hits the particular exotic regions of that world. Once Asia, Africa and North America continents have been this Dengue strain and temperature areas. Lateron the Dengue traveled to Jakarta, Indonesia, Cairo, Egypt and Philadelphia. SYMPTOMS OF DENGUE FEVER. Dengue fever signs or symptoms will be different as per time on the patients. Infants plus small children should experience that curse having rash. Adults and also adolescent children though including that dengue fever, complain because suffering from regimen seasonal or perhaps acute fever along with headache, ache lurking behind your eyes, muscle mass and also joint capsules pain and rash. TREATMENT OF DENGUE. There is actually no certain treatment involving dengue fever. Simple remedies which have been used in intense or ache associated with several aspects of body, will be proposed while in your dengue fever. If internal bleeding will there be over the dengue fever, it's caused by decreased platelet count, with time platelet concentrates and also purple cell phone transfusion need to be at this time there out of time to time up until 2 or 3 weeks. PREVENTIONS OF DENGUE VIRUS. If we help save ourself coming from the actual bite regarding mosquito we're successful avoiding this dengue or maybe different trojan in the bite of mosquito as the solely cause of dengue is the mosquito bite. Mosquito repellant, defensive clothing and also windows woven screens could be helpful. Pollution similar to water-filled things in addition to good old auto tires must not often be there inside vicinity.



Dengue Symptoms as well as Treatments in order to Stay Healthy

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Dengue a fever will be a great contagious tropical disease (a flu-like health issues pass on by the bite of the afflicted mosquito) attributable to among the three carefully related trojans specifically DEN-1, DEN-2, DEN-3 and also DEN-4. The Aedes aegypti mosquito will be the greatest carrier of dengue viruses. The mosquito gets infected with dengue malware whenever it bites people by using dengue fever. It is not really transmitted specifically from one individual to help another. Dengue a fever could be deadly whenever unknown plus poorly treated. This disorder must end up being treated whenever the particular Dengue signs or symptoms are diagnosed. The death out of Dengue fever is often below 1% if excellent health care is actually employed. There are usually dengue treatments out there which might be effective. How do people get infected? The critical details for being kept in mind regarding cause of illness are: 1. Humans get infected themselves solely from the bite of an afflicted mosquito 2. Not transmitted specifically from one particular human being for you to another 3. Symptoms with dengue fever 4. High fever 5. Severe headache 6. Backache 7. Joint pain 8. Nausea 9. Vomiting 10. Eye pain 11. Rash Treatments and medicine available There can be precise dengue therapy readily available dengue fever. The people having dengue should utilize analgesics (pain relievers) using acetaminophen in addition to avoid those people that contain aspirin. But whenever quick diagnosis created from then dengue curse could be effectively treated with smooth replacing treatments which is drink an abundance of fluids, seek health-related assistance plus have rest. google_ad_client = "pub-2311940475806896"; /* 300x250, made 1/6/11 */ google_ad_slot = "0098904308"; google_ad_width = 300; google_ad_height = 250; Sometimes hospitalization is required to treat the following disease. As for each your dengue symptoms, individuals should have the treatment. Preventive measures 1. Use mosquito repellants on skin 2. Wear longer sleeved shirts and also longer jeans in the course of moments any time mosquitoes are biting 3. Use bed netting though sleeping 4. Water with coolers should be supplanted regularly 5. Items where rain water receives collected must be discarded 6. Infected person must always be kept faraway from mosquitoes 7. Avoid heavily populated residential areas 8. Take a good deal connected with fluids 9. The habitats of the mosquitoes need to be removed making use of neurological handle agents 10. Consult your physician when signs involving dengue appear Even your quickest symptoms ought not possibly be neglected. Though the actual fatality from this disease is incredibly low nevertheless the tiniest carelessness may be fatal. People should come in cognizant of that dengue signs and symptoms plus they have to move to be able to right dengue treatment absolutely no sooner your indications tend to be discovered. Infected person's need to be kept away from mosquitoes so that many people tend not to have infected. With these simple points with mind, dispersion associated with dengue intense is often fended off in the end �prevention can be as good as cure�.



Dengue in addition to Swine Flu Causes and Symptoms plus pure Treatment associated with Dengue and Swine Flu

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Dengue curse is a disease the result of children associated with trojans which can be transported by simply mosquitoes. It is an acute health problems of abrupt onset that will generally follows a benign training course using indications just like headache, fever, exhaustion, serious muscles plus synovial pain, irritated glands (lymphadenopathy), along with rash. The presence (the "dengue triad") of fever, rash, as well as head ache (and various other pains) can be in particular trait of dengue. Other symptoms with dengue fever include hemorrhaging gums, severe soreness at the rear of that eyes, and reddish colored palms plus soles. Read extra on Herbal Remedies pertaining to Swine Flu along with Swami Ramdev Yoga along with Swami Ramdev Medicines What Causes Dengue Fever? Dengue temperature might be the result of just about any one among four different types of dengue virus: DEN-1, DEN-2, DEN-3, along with DEN-4. Infection having one computer virus isn't going to protect people versus infection with another. A particular person may be contaminated simply by at the very least two, or else many several sorts of the particular dengue malware at numerous moments by carrying out a your life span, although just one time through the exact same type. Symptoms with Dengue 1. google_ad_client = "pub-2311940475806896"; /* 300x250, made 1/6/11 */ google_ad_slot = "0098904308"; google_ad_width = 300; google_ad_height = 250; Severe headache 2. Pain lurking behind that eye 3. Severe combined pain 4. Severe muscle pain 5. Nausea 6. Rash Treatment involving Dengue The first action in the treatment of dengue fever is prevention. Prevention measures comprise avoiding mosquito populations throughout nice sub-tropical and exotic instances of the world. This includes draining places and also materials which could carry place water plus become a new propagation floor for mosquitoes, like aged tires, puddles, along with chicken baths. Wearing pest repellent which contains DEET, picaridin, or perhaps oil with lemon eucalyptus plus being dressed in shielding clothes that handles the full body are usually also important preventive measures. There is usually very little particular therapy with regard to or maybe vaccine to be able to prevent dengue fever. Most individuals who get dengue a fever will probably recover within with regards to 2 weeks to a four week period simply by getting plenty of rest, increasing fluid intake plus getting acetaminophen (Tylenol) with regard to curse and also system aches. People with dengue a fever probably should not consider aspirin or even medicines that have aspirin given it heightens the risk intended for serious bleeding. Swine Flu Swine flu has been creating a terror consequences all round the world as well as has been announced epidemic in most a part of your world. This is actually caused by influenza A (H1N1) virus. Swine Flu is H1N1, or pig influenza - a strong acute respiratory infection, usually affects pigs, nonetheless the capability that will pounce plus man. Presumably, alcoholism made an appearance after the puppy is definitely grabbed one particular of a number of kinds of the herpes simplex virus - the latest strain, experts have determined records connected with the particular North American pig flu or swine flu, the particular North American avian influenza, in addition to swine and individual computer virus commonly found in Asia and Europe. The initial cases of human being illness by pathogen documented on 18 March in Mexico. What are Swine Flu symptoms? 1. High temperature 2. Cough 3. Shortness of breath, Feel Trouble within breathing Home Remedies to get Swine Flu 1. Regularly ventilated area, carry out soaked cleaning, rinse the hands frequently. 2. Strengthen your current immune : system, far more usually outdoors, step more. 3. Before dating into the block or even within open public places include nostril - the idea has antiviral activity versus influenza. 4. Try to help keep away from communication with ill people. If that is unavoidable, put on respirators or gauze dressing. 5. After working together with raw meat, Wash your current arms carefully. Do possibly not eat diet or half-meat. Porcine influenza virus, just like any pathogen is definitely messed up at the temperature associated with 65 degrees. Disinfectants obliterate the pup instantly.



The Symptoms And Preventive Measures Of Dengue

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Dengue can be a condition attributable to worms that will will be transported by way of mosquito (Aedes aegypti ) bite. The Dengue causing mosquito is actually observed while in damp seasons however can reproduce in water-filled pots, wasteland coolers, and aged tires. Dengue symptoms can easily occur to people of almost all ages but it surely typically has an effect on babies within the actual time with 15 years. Dengue Symptoms * Chills * Fever * Headache * Rashes to the biceps in addition to feet in the beginning after which you can distribution to the abdomen, torso and back. * Flushed face * Lower backache and weakness * Redness plus agony inside eyes * Severe muscular and also combined pain * Swelling with lymph nodes All these types of Dengue indicators decrease inside of 2-3 nights plus at a later date patient things major sweating. Dengue is also also known as Break bone fragments Fever since the individuals regarding Dengue usually have serious signs and symptoms regarding rigorous synovial and also lean muscle pain. In worse cases, persons include signs or symptoms like excessive intense and also headache. The dengue virus causes this puffiness and also leakage associated with blood vessels in addition to generates little purple coloured places to the skin. Bleeding into your tummy causes extreme abdominal aches and pains and also vomiting. The ruined leading to tinnitus eventually become so large them to are unable to provide the needed flow as well as breathable oxygen this holds to the body's tissues. Due for you to this particular dengue warning sign the body to search towards shock, that will deterioration main internal organs including coronary heart as well as kidneys. Prevention Prevention is definitely greater than cure; it is a classic age saying which stands very true for Dengue prevention. google_ad_client = "pub-2311940475806896"; /* 300x250, produced 1/6/11 */ google_ad_slot = "0098904308"; google_ad_width = 300; google_ad_height = 250; For Dengue prevention, this procreation regarding it has the vector, the actual Aedes mosquito ought to be prevented. The Aedes mosquito is named simply by it has the paper stripes. It breeds throughout clean, stagnant water easily present in our homes hence we ought to be certain that will drinking water storage containers will be protected to forestall breeding connected with mosquitoes. Dengue mosquito usually bites daily thus we should guard yourself on the mouthful through wearing full-sleeve garments or maybe long garments to pay that arms and also lower-leg intended for Dengue prevention. We may also work with repellents mosquito coils in addition to electric powered vapor mats in the daytime for Dengue prevention. If there are declared Dengue situations from the neighborhood, next we could apply your aerosol insecticides inside the 4 corners of properties to destroy that adult mosquitoes in your resting state while in the corners if at all possible through early morning.



The Symptoms and also Preventive Measures with Dengue - Health - Diseases and Conditions

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Dengue is usually a sickness brought on by infections which are transmitted through mosquito (Aedes aegypti ) bite. The Dengue causing mosquito is usually discovered while in stormy months although can certainly particular breed of dog throughout water-filled pots, wilderness coolers, and old tires.

Dengue symptoms can easily happen in order to people of all ages but it mostly affects kids below the age group of 15 years.

Dengue Symptoms

* Chills* Fever * Headache* Rashes on the biceps and triceps as well as legs at first after which it spreading towards abdomen, chest along with back.* Flushed face* Lower backache along with weakness* Redness along with agony in eyes* Severe muscular in addition to shared pain* Swelling within lymph nodes

All most of these Dengue signs diminish within 2-3 days and nights and also at a later date person experiences major sweating.

Dengue will be often known as Break bone Fever since the patients involving Dengue typically have critical signs and symptoms connected with intense bowl and also muscle mass pain.

In more severe cases, persons have symptoms like large fever and also headache. The dengue pathogen creates the particular lump as well as loss of bloodstream and generates smaller blue colored spots within the skin. Bleeding in to the stomach will cause serious abdominal pains as well as vomiting. The broken continue vessels finally come to be so huge potentially they are struggles to source the needed the flow of blood and the breathable air it provides on the body's tissues. Due to that dengue symptom your body to visit directly into shock, and damages major organs including the cardiovascular system and kidneys.

Prevention

Prevention is always better as compared with cure; this is a classic age group telling that stalls really correct to get Dengue prevention. For Dengue prevention, the actual breeding of it's vector, the particular Aedes mosquito should often be prevented. The Aedes mosquito can be distinguished by means of it is black and white stripes. It breeds with clean, flat waters effortlessly obtained in some of our houses consequently we ought to ensure that normal water storage canisters are generally dealt with to stop proliferation of mosquitoes. Dengue mosquito normally gnaws during the day so most people need to protect themselves from your mouthful by wearing full-sleeve outfits or maybe long dresses to help cover your hands and wrists and lower calf to get Dengue Prevention.

We also can use repellents mosquito coils along with electric vapor mats in the daytime for Dengue prevention. If there are diagnosed Dengue situations in the neighborhood, subsequently you can easlily spray that aerosol insecticides from the sides involving residences for you to kill the older mosquitoes sleeping inside the aspects ideally during first morning.

To realize much more related to Dengue Prevention, Dengue and Symptoms regarding Dengue go to onlymyhealth.com





26 Eylül 2012 Çarşamba

Immunotherapy - top articles for August 2012

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Here are my suggestions for some of the top articles about immunotherapy for August 2012:

Immunotherapy prescribed for 5 years by 75% of US-Canadian allergists, for 3 years by the rest of the world http://goo.gl/K0Cr7

Intralymphatic immunotherapy for cat allergy induces tolerance after only 3 injections - first human study ILIT with MAT–Fel d 1 http://goo.gl/jHAe9

Eosinophilic esophagitis induced by milk oral immunotherapy - 3 case reports http://goo.gl/NHljN

Allergen immunotherapy is a cost-effective treatment in modifying existing allergic respiratory diseases - Chest 2012 http://goo.gl/GdkbH

Therapies for allergic inflammation: refining strategies to induce tolerance - Nature Medicine 2012 review, full text http://goo.gl/te9XM

Fear needles? Looking away while you're getting an injection makes it hurt less (study) http://goo.gl/k7NSi

Allergen immunotherapy causes production of high-affinity allergen-specific blocking IgG(4) http://goo.gl/FvR0Z

Safety of Allergen Immunotherapy - 2012 Medscape review http://goo.gl/0ZsVx

Epinephrine in the treatment of anaphylaxis. Adult intramuscular dose is 0.3 to 0.5 ml of 1:1,000 concentration http://goo.gl/Qad6S

To expect clinical efficacy from SLIT for allergic rhinitis, sufficiently high doses have to be regularly administered for at least 3 consecutive years http://goo.gl/kl8Xx

Allergy shots: Do patients feel pain or fear? http://goo.gl/MlczE - Full text PDF: http://goo.gl/SVtLp

"Beat Allergies Drop by Drop" - WSJ - However, most insurers don't cover SLIT cost, typically $30-150/month http://goo.gl/71W2s

The articles were selected from my Twitter stream @Allergy and Google Reader RSS subscriptions. Some of the top allergy accounts on Twitter contributed links. I appreciate the curation provided by @JuanCIvancevich @AllergyNet @IgECPD4 @DrAnneEllis @AACMaven @AllergieVoeding @allergistmommy @mrathkopf @wheezemd.

Please feel free to send suggestions for articles to allergycases@gmail.com and you will receive acknowledgement in the next edition of this publication.

Image source: OpenClipArt.org, public domain.

Effect of childhood asthma and inhaled steroid on adult height: 1.2 cm lower height with budesonide vs. placebo

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The use of inhaled glucocorticoids (ICS) for persistent asthma causes a temporary reduction in growth velocity in prepubertal children. The resulting decrease in attained height 1 to 4 years after the initiation of inhaled glucocorticoids is thought not to decrease attained adult height.

This study published in the NEJM measured adult height in 943 participants in the Childhood Asthma Management Program (CAMP) at age 25. Starting at the age of 5 to 13 years, the participants had been randomly assigned to receive 400 μg of budesonide, 16 mg of nedocromil (not available in the U.S. since 2010), or placebo daily for 4 to 6 years.

Mean adult height was 1.2 cm lower in the budesonide group than in the placebo group (P=0.001) and was 0.2 cm lower in the nedocromil group than in the placebo group. A larger daily dose of inhaled glucocorticoid in the first 2 years was associated with a lower adult height (−0.1 cm for each microgram per kilogram of body weight) (P=0.007). The difference between ICS and placebo was noted only during the first two years of therapy and it was not progressive.

The initial decrease in attained height associated with the use of inhaled glucocorticoids in prepubertal children persisted as a reduction in adult height, although the decrease was not progressive or cumulative.

Editor's note: This study shows that more severe asthma that requires treatment with ICS is associated with lower height as an adult. Many chronic diseases during childhood affect adult height and asthma is no exception. A longer time since asthma diagnosis and atopy (any positive skin test) were independent risk factors for shorter adult height. When asthma and atopy impair growth, the deficit may persist into adulthood. The conclusion is not to "stop" the use of ICS but to use the lowest effective ICS dose for symptom control, which is in agreement with the current asthma guidelines.

By the way, the findings of the 2012 study in the NEJM contradict a 2000 study published in the same journal that did not show an effect of ICS on growth (Effect of Long-Term Treatment with Inhaled Budesonide on Adult Height in Children with Asthma - NEJM http://goo.gl/qM3Nf).



Asthma Inhalers (click to enlarge the image).

Comments by other physicians:

This article is an attempts to address sensational headlines (http://bit.ly/RLkhSv) such as: "Everybody Panic: Asthma Inhalers May Stunt Growth Permanently", "Asthma Drug Stunts Kids' Height for Life", "Asthma drug may stunt growth permanently", "Study: Asthma medications make you short", etc.

The benefits of ICS in asthma far outweigh a slight decrease in height. However, when compared with placebo and nedocromil, the effect of budesonide is demonstrated as a cause of reduced stature, since all patients were also asthmatic and atopic.

In the paper all the patientes were mild-to-moderate asthma, although the authors didn't take into account the difference of severity of asthma between groups, patients were randomly assigned to the three treatment groups and the differences between the groups were significant.

Andrew S Nickels, MD:

Looking at the original Childhood Asthma Management Program (CAMP) cohort, the baseline characteristics that are reported seem matched, which would suggest adequate randomization. (1) One lacking aspect of initial enrollment demographics in the original trial cohort is the initial tanner staging being reported. This is pointed out by Mary Ellen Wohl and Joseph A Majzoub in their editorial response to the initial trial.(2) This seems a crucial baseline statistic when assessing growth velocity and final height.

However, while the cohorts may have been similar at baseline, there were significant differences between the inhaled Budesonide and Placebo groups in regards to several outcomes. These include the following: course of oral Prednisone (70/100 person-years vs 122/100 person-years, P below 0.0001), Urgent care visits due to asthma (12/100 person-years vs 22/100 person-years, P below 0.0001), and Hospitalizations due to asthma (2.5/100 person-years vs 4.4100 person-years, p = 0.04). (1) Intuitively, one would expect the higher burden of asthma morbidity felt by the placebo group would negatively effect height,
but that conclusion is outside of the scope of these investigations. As pointed out by Wohl and Majzoub, growth is a complex and poorly understood process. (2) This study outlines a loose association at best between two groups whose developmental years are dissimilar. A larger cohort would be needed with tighter subgroup analysis to tease out this finding. This will be limited by the unethical nature of enrolling known asthmatic children in placebo control trials. (3)

1. The Childhood Asthma Management Program Research Group. Long Term Effects of Budesonide or Nedocromil in Children with Asthma. N Engl J Med 2000; 343:1054-1063.

2. Wohl M, Majzoub J. Asthma, Steroids, and Growth. N Engl J Med 2000; 343:1113-1114.

3. Coffey MJ, Wilfond B, Ross LF. Ethical assessment of clinical asthma trials including children subjects. Pediatrics. 2004; 113: 87-94

References:

Effect of Inhaled Glucocorticoids in Childhood on Adult Height. H. William Kelly, Pharm.D., Alice L. Sternberg, Sc.M., Rachel Lescher, M.D., Anne L. Fuhlbrigge, M.D., Paul Williams, M.D., Robert S. Zeiger, M.D., Ph.D., Hengameh H. Raissy, Pharm.D., Mark L. Van Natta, M.H.S., James Tonascia, Ph.D., and Robert C. Strunk, M.D. for the CAMP Research Group, September 3, 2012 (10.1056/NEJMoa1203229) (free full text).

Inhaling steroids stunts growth, but not much. "This is mostly good news. Now we know what it is. It is a half an inch" | Reuters  http://goo.gl/zkTpc

Image source: Image source: FDA and Wikipedia, public domain.